Cat. No.: GENE1729

CCNK

Description Cyclin K
Category Protein Coding
GIFtS 42
GC id GC14P099483
Score 6.04
Entrez Gene Summary The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008]
GeneCards Summary CCNK (Cyclin K) is a Protein Coding gene. Diseases associated with CCNK include Intellectual Developmental Disorder With Hypertelorism And Distinctive Facies and Ccnk-Related Neurodevelopmental Disorder-Severe Intellectual Disability-Facial Dysmorphism Syndrome. Among its related pathways are HIV Transcription Elongation and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include protein kinase binding and RNA polymerase II CTD heptapeptide repeat kinase activity. An important paralog of this gene is CCNT2.
Gene Database GeneCards: The Human Gene Database
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