| Description | Telomeric Repeat Binding Factor 2 |
| Category | Protein Coding |
| GIFtS | 40 |
| GC id | GC16M069355 |
| Score | 7.75 |
| Entrez Gene Summary | This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008] |
| GeneCards Summary | TERF2 (Telomeric Repeat Binding Factor 2) is a Protein Coding gene. Diseases associated with TERF2 include Werner Syndrome and Nijmegen Breakage Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and DNA Damage. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein C-terminus binding. An important paralog of this gene is TERF1. |
| Gene Database | GeneCards: The Human Gene Database |
| Price | Inquiry |
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